The Hyperactivation of JAK-STAT Signaling Connects Inborn Errors of Immunity and Autoimmune Diseases
JAK-STAT signaling pathway is an important cytokine signaling transduction pathway.Many monogenic loss-of-function or gain-of-function mutations in this pathway can Sideboard cause inborn errors of immunity (IEI).Autoimmune diseases are caused by polygenic and different factors.The etiology of the disease is complex and diverse.The over-activation